Multiple sclerosis (MS) is chronic progressive, disabling demyelinating, neuroinflammatory and neurodegenerative disorder of the central nervous system (CNS) for which the primary cause is yet unknown. While MS manifests as a disease with distinct disease courses, (ongoing) demyelination and EBV infection are among others common denominators. In this project, we will examine whether EBV infection brought into the CNS by B cells is directly linked to loss of cells that produce myelin (oligodendrocytes) and demyelination, and therefore at the basis of the onset of MS. Elucidation of the cell biological mechanism underlying this novel principle on the cause of MS will provide new targets for therapeutic intervention that may prevent further development of MS.
The project will be performed in close collaboration with Dr. Sander van Kasteren (Leiden University). The position is funded by Stichting MS Research and is made possible by MoveS.
What do we need
A research technician with a BSc or MSc degree in Life Sciences (Biomedical Sciences, Cell Biology, Neurosciences). We are looking for someone that has proven technical skills with tissue and primary cell cultures. Expertise with imaging will be an advantage. Furthermore, you will need a flexible working attitude, team player mentality, good communication skills and a pro-active attitude.
The UMCG has a preventive Hepatitis B policy. The UMCG can provide you with the vaccination, should it be required for your position.
In case of specific professions a ‘Certificate of Good Conduct’ is required.
What do we offer
A temporary contract of one year (0,8 fte). Preferably starting September 1, 2020. Your salary will be a maximum of € 3.280,- gross per month (scale 7), depending on your qualifications and relevant experience, based on a full-time appointment. In addition, the UMCG will offer you 8% holiday pay, and 8.3% end-of-year bonus. The conditions of employment comply with the Collective Labour Agreement for Medical Centres (CAO-UMC). English: http://www.nfu.nl/english/about-the-nfu/